I ended up updating and the new serum file on scared stiff looks great.
Tron on the other hand doesn't display correctly, its legible but it doesn't look right. I re downloaded the colour file and the ROM, no luck
To update I installed VPinMame 3.5, both x86 and x64. Run the install on x86
Installed Freezy 2.0, updated DMDdevice.ini
Installed lucky1's dll files from this file: dmd-extensions_with_pin2color_and_serum_plugin.zip. Downloaded from VPU
All of my other colour ROMS are working.
We'll see if my installation is OK when more serum files come out, hopefully the Tron one is a once off